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Product Name: | Amlodipine besilate | Chinese Name: | Benhuangsunlvandiping |
CAS NO: | 111470-99-6 | Other Name: | 4-dihydropyridine benzenesulfonate |
MF: | C26H31ClN2O8S | MW: | 567.05 |
Assay: | 98% | Test Method: | HPLC |
Appearance: | White to almost white powder. | ||
Physical Property: | Melting Point 199-201℃.Slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol and slightly soluble in 2-propanol. | ||
Function: | Amlodipine has been demonstrated to block constriction and restore blood flow in coronary arteries and arterioles in response to calcium, potassium epinephrine, serotonin, and thromboxane A2 analog in experimental animal models and in human coronary vessels in vitro. This inhibition of coronary spasm is responsible for the effectiveness of amlodipine in vasospastic (Prinzmetal's or variant) angina. |
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